In the British Medical Journal (subscription required) Dalrymple reviews a bad but interesting novel:

Wilkie Collins (1824-1889) was addicted to laudanum (tincture of opium in alcohol) for much of his life, but that did not prevent him from producing a vast corpus of work. Among his novels is Heart and Science, published in 1883, known (in so far it is known at all) for its protest against vivisection.

It is not a good novel, to put it mildly, and it would take several pages of convoluted prose to summarise its preposterous plot. But it has much, from character to incident, to interest the medical reader.

….

Heart and Science is not so much an attack on science as on the supposed all-sufficiency of science; it is not very effective, however, because it is such a bad book.